Journal of Dental Sciences
Volume 5, Issue 1 , Pages 30-35 , March 2010

Enhancement of 5-aminolevulinic acid-induced photodynamic therapy by a bioadhesive polymer

  • Shu-Fang Chang

      Affiliations

    • Department of Dentistry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan
    • ,
  • Yu-Tsai Yang

      Affiliations

    • College of Oral Medicine, Taipei Medical University, Taipei, Taiwan
    • ,
  • Wei-Ling Li

      Affiliations

    • Graduate Institute of Biomedical Materials and Engineering, Taipei Medical University, Taipei, Taiwan
    • ,
  • Che-Tong Lin

      Affiliations

    • College of Oral Medicine, Taipei Medical University, Taipei, Taiwan
    • ,
  • Tsuimin Tsai

      Affiliations

    • College of Oral Medicine, Taipei Medical University, Taipei, Taiwan
    • Graduate Institute of Biomedical Materials and Engineering, Taipei Medical University, Taipei, Taiwan
    • Corresponding Author InformationCorresponding author. Graduate Institute of Biomedical Materials and Engineering, Taipei Medical University, 250, Wu-Hsing Street, Taipei 11042, Taiwan

Received 14 November 2009 ,Accepted 20 February 2010.

References 

  1. Malik Z , Lugaci H . Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins . Br J Cancer . 1987;56:589–595
  2. Divaris DX , Kennedy JC , Pottier RH . Phototoxic damage to sebaceous glands and hair follicles of mice after systemic administration of 5-aminolevulinic acid correlates with localized protoporphyrin IX fluorescence . Am J Pathol . 1990;136:891–897
  3. Peng Q , Warloe T , Berg K , Moan J , Kongshaug M . 5-Aminolevulinic acid-based photodynamic therapy: clinical research and future challenges . Cancer . 1997;79:2282–2308
  4. Dolmans DE , Fukumura D , Jain RK . Photodynamic therapy for cancer . Nat Rev Cancer . 2003;3:380–387
  5. Henderson BW , Dougherty TJ . How does photodynamic therapy work? . Photochem Photobiol . 1992;55:145–157
  6. Hillemanns P , Weingandt H , Baumgartner R , Diebold J , Xiang W , Stepp H . Photodetection of cervical intraepithelial neoplasia using 5-aminolevulinic acid-induced porphyrin fluorescence . Cancer . 2000;88:2275–2282
  7. Levulan Kerastick (aminolevulinic acid HCl) for topical solution, 20% . Available at: http://www.icare.org/fda.htm
  8. Tsai JC , Chiang CP , Chen HM , et al.   Photodynamic therapy of oral dysplasia with topical 5-aminolevulinic acid and lightemitting diode array . Lasers Surg Med . 2004;34:18–24
  9. Chen HM , Chen CT , Yang H , et al.   Successful treatment of oral verrucous hyperplasia with topical 5-aminolevulinic acid-mediated photodynamic therapy . Oral Oncol . 2004;40:630–637
  10. Yu CH , Chen HM , Hung HY , Cheng SJ , Tsai T , Chiang CP . Photodynamic therapy outcome for oral verrucous hyperplasia depends on the clinical appearance, size, color, epithelial dysplasia, and surface keratin thickness of the lesion . Oral Oncol . 2008;44:595–600
  11. Chien HF , Liao YH , Chen CT . Topical 5-aminolevulinic acid photodynamic therapy for warts . Lasers Surg Med . 2007;39(S19):57
  12. Wang YS , Tay YK , Kwok C , Tan E . Photodynamic therapy with 20% aminolevulinic acid for the treatment of recalcitrant viral warts in an Asian population . Int J Dermatol . 2007;46:1180–1184
  13. Duncan R . The dawning era of polymer therapeutics . Nat Rev Drug Discov . 2003;2:347–360
  14. Pharmaceutical Ingredients. Lubrizol Web site . http://www.lubrizol.com/Pharmaceutical/default.html
  15. Gerlier D , Thomasset N . Use of MTT colorimetric assay to measure cell activation . J Immunol Methods . 1986;94:57–63
  16. Gibson SL , Nguyen ML , Havens JJ , Barbarin A , Hilf R . Relationship of delta-aminolevulinic acid-induced protoporphyrin IX levels to mitochondrial content in neoplastic cells in vitro . Biochem Biophys Res Commun . 1999;265:315–321
  17. Masters JR . False cell lines: the problem and a solution . Cytotechnology . 2002;39:69–74
  18. Fuerte V , Maldonado M , Rees GD . The multicomponent automated dissolution system: an alternative in the development and pharmaceutical analysis of generic polydrugs . J Pharm Biomed Anal . 1999;21:267–272

PII: S1991-7902(10)60005-0

doi: 10.1016/S1991-7902(10)60005-0

Journal of Dental Sciences
Volume 5, Issue 1 , Pages 30-35 , March 2010

Article Tools